The Cougar XR7 was again matched with the Thunderbird, with the standard Cougar becoming the counterpart of the Ford Granada (replacing the Mercury Monarch). The fourth generation was split into two model lines the Cougar replaced the Montego (matching the Ford LTD II), with the Cougar XR7 paired with the Ford Thunderbird.įor its fifth and sixth generations, the Cougar was downsized, adopting the compact Fox chassis. Slotted above the Montego, the Cougar became the counterpart of the Ford (Gran Torino) Elite. Initially developed as a pony car, it replaced the Cyclone muscle car in the Mercury model line.įor its third and fourth generations, the Cougar adopted the chassis of the Ford Torino intermediate. The models were distinguished by an exterior ranging in degree from grilles and lighting components to nearly the entire exterior, the Cougar shared its platform with Ford vehicles throughout its production.įor its first two generations, the Cougar was derived from the Ford Mustang. Overview Mercury Cougar emblem (1970 Cougar Eliminator)ĭuring much of its production, the Cougar followed tradition within the Mercury division, marketed as a Mercury counterpart of a Ford vehicle. Cat-related nameplates were adopted by the division such as the Bobcat and Lynx.ĭuring its production, the Cougar was assembled at the Dearborn Assembly Plant (part of the Ford River Rouge Complex) in Dearborn, Michigan from 1967 until 1973, San Jose Assembly ( Milpitas, California) from 1968 into early 1969, Lorain Assembly ( Lorain, Ohio) from 1974 until 1997, and at Flat Rock Assembly ( Flat Rock, Michigan) from 1999 through 2002. During the 1970s and 1980s, the Cougar was closely tied to the marketing of the Mercury division Mercury advertised its dealers as "The Sign of the Cat" with big cats atop Lincoln-Mercury dealer signs. With 2,972,784 examples produced, the Cougar was the highest-selling nameplate produced by the Mercury brand its 34-year production is second only to the Grand Marquis in the Mercury model line (made for 36 years). While the nameplate is associated with two-door coupes, at various times during its production, the Cougar was also marketed as a convertible, four-door sedan, station wagon, and a hatchback. Mercury Cougar is a nameplate applied to a diverse series of automobiles sold by the Mercury division of Ford from 1967 until 1997 and from 1999 through 2002 model years. Transverse front-engine, front-wheel drive (1999–2002)
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Let's use keywords and modifier functions interchangeably to perform some common modifications to our example, listed below. We can apply it to other plot objects via attribute!(p, value), where p is the name of the plot object that wants to be modified. This will implicitly use the global Plots.CURRENT_PLOT. xlabel!("x")Įvery modifier function is the name of the attribute followed by !. It's up to you to decide which is better for code readability. We can specify it in the plot command with xlabel=., or we can use the modifier function below to add it after the plot has already been generated. For example, the xlabel attribute adds a label for the x-axis. Some attributes have their own dedicated modifier functions, while others can be accessed through plot!(attribute=value). Plot(x,, title="Trigonometric functions", label=, linewidth=3)Įvery attribute can also be applied by mutating the plot with a modifier function. Let's apply all of this to our previous plot: x = range(0, 10, length=100) Additionally, since the line width is being attributed to, both lines will be affected by the assigned value. Notice how has the same number of columns as the data. So something like plot(x, y, z) is three-dimensional data for 3D plots with no attributes, while plot(x, y, attribute=value) is two-dimensional data with one attribute assigned to some value.Īs an example, we can change the line width using linewidth (or its alias lw), change the legend's labels using label, and add a title with title. Keyword arguments correspond to attributes.Positional arguments correspond to input data.Plots.jl follows two simple rules with data and attributes: In Plots.jl, the modifiers to plots are called attributes, which are documented at the attributes page. we're done, right? No! We need to style our plots. More information about outputting figures can be found in the Output section of the Manual. The following is equivalent to the above code: png("myplot") With these, the extension is omitted from the filename. There also exist convenience functions png, Plots.pdf and other unexported helpers. Savefig(p, "myplot.pdf") # saves the plot from p as a. For example: savefig("myplot.png") # saves the CURRENT_PLOT as a. Saving plots is done by the savefig command. In cases where the plot variable is omitted, Plots.jl uses the global Plots.CURRENT_PLOT automatically. Note that we could have done the same as above using an explicit plot variable, which we call p: x = range(0, 10, length=100) If we inputted the dots manually, we would need three of them for the sine, exponent, and subtraction, and the resulting code would be less readable. This is a convenience macro that inserts dots for every function call to the right of the macro, ensuring that the entire expression is to be evaluated in an element-wise manner. This is done by the plot! command, where the ! denotes that the command is modifying the current plot. x = range(0, 10, length=100)Īdditionally, we can add more lines by mutating the plot object. Below, forms a 100x2 matrix (100 elements, 2 columns). We can plot multiple lines by plotting a matrix of values where each column is interpreted as a separate line. In Plots.jl, every column is a series, a set of related points which form lines, surfaces, or other plotting primitives. Because of the way Julia works under the hood, this is a difficult problem to solve, but much progress has been made in the past few years to reduce this compilation time. If this is your first plot of the session and it takes a while to show up, this is normal this latency is called the "time to first plot" problem (or TTFP), and subsequent plots will be fast. The plot is displayed in a plot pane, a stand-alone window or the browser, depending on the environment and backend (see below). To do this in Julia, we insert a dot right after the function call. For the y coordinates, we can create a vector by evaluating sin(x) in an element-wise fashion. For the x coordinates, we can create a range from 0 to 10 of, say, 100 elements. To start, let's plot some trigonometric functions. Depending on your computer, this will take a few seconds: using Plots Basic Plotting: Line PlotsĪfter you have installed Plots.jl via Pkg.add("Plots"), the first step is to initialize the package. It is recommended that the code examples be followed inside the REPL or an interactive notebook. Its main goal is to introduce you to the terminology used in the package, how to use Plots.jl in common use cases, and put you in a position to easily understand the rest of the manual. This is a guide for getting you up and running with Plots.jl. The CVMP Pharmacovigilance Working Party (PhVWP-V) provides advice to the Committee for Veterinary Medicinal Products (CVMP) and the Coordination group for mutual recognition and decentralised procedures for veterinary medicinal products (CMDv) on coordinating and overseeing veterinary pharmacovigilance activities in the EU / EEA. The European Medicines Agency (EMA) is preparing scientific and technical recommendations to feed into delegated and implementing acts as part of the. University Animal Hospital Academic Conferences Collaborative centres and. With pawlidays pet photos, treats and gifts for our four-legged friends. Veterinary medicines exempt from authorisation under Article 5(6) of Regulation (EU) 2019/6 Contacts - EMA Show navigation links for Kontakta en miljanalytiker. The European Medicines Agency (EMA) provides guidance and support to companies researching and developing veterinary medicines. 1628A Belle View Boulevard, Alexandria, Virginia 22307.Registered homeopathic veterinary medicines.The system is applicable to all veterinary medicines in the EU / European Economic Area, including: Suspected spread of an infectious agent by a medicine.Lack of efficacy or adverse events when a medicine is used off-label Spread over two half-days, this event is designed to provide updates on topics such as regulatory policy, scientific and procedural developments and receive.The late vet was part of the first Canadian figure skating pair to win both Olympic. Suzanne Morrow (Francis) Suzanne Morrow (nee Francis), was not only a renowned figure skater but also a veterinarian and All-Breed dog show judge. The EU pharmacovigilance system involves continuous safety monitoring by identifying and analysing any negative effects from the use of veterinary medicines that may occur in animals. The European Surveillance of Veterinary Antimicrobial Consumption (ESVAC) project collected information from 2009 to 2023 on how antimicrobial medicines are used in animals across the European Union (EU). Here are 9 female veterinarians who have become quite notable for cool, amazing, and even infamous reasons. You’ll still find two ways to login via Windows 10 Hello, an infrared camera for facial recognition and a fingerprint scanner. And while you can bend the lid a bit if you try hard enough, there’s no flex in the keyboard deck or chassis bottom, ranking it close to the tank-like Yoga C930 in rigidity.Īs if that wasn’t enough, HP has also improved the Spectre x360’s security features. HP seems to think you’ll want something to hold onto in portrait tablet mode, and they’re not wrong. Of course, this is a 2-in-1, so while its side bezels are relatively thin, the top and bottom bezels can’t compare to the ones on more diminutive clamshell laptops like the Dell XPS 13. The Spectre x360 remains light enough at 2.92 pounds compared to the Lenovo at 3.0 pounds and the Gram 14 at a featherweight 2.5 pounds. Both of those 2-in-1s sport 14-inch displays, but they’re nevertheless the best comparisons. The laptop is now 0.57 inches thick, compared to the Yoga C930 at an identical 0.57 inches and the LG Gram 14 at 0.70 inches. The new Spectre x360 is nicknamed the “gem-cut” model, and for a good reason.Īnother functional change is that HP made the Spectre x360 0.9mm thicker, which isn’t enough to notice but allows for better thermal performance. There’s nothing else like it and other 2-in-1s, such as the LG Gram 14 and the Lenovo Yoga C930, look downright boring with their simplistic designs and muted colors. I love the look, though I recognize that some people might consider it a bit much. Even the speaker grills have an angular pattern. The edges of the lid, the chassis sides, the border around the keyboard deck, the chassis bottom – they’re all angled, in much the same way as a precious stone. Every facet has been shaped to reflect light from as many angles as possible. HP has nicknamed this Spectre x360 the “gem-cut” model, and that’s for a good reason. Did they manage to make something great even better, or did they kill the magic? An exotic design that’s built well and turns heads This new model makes major changes to my favorite 2-in-1, and HP is asking a premium for it. HP’s new Envy x360 14 looks like a killer value for what you getĪsus ZenBook S 13 Flip vs. The ThinkPad X1 Carbon Gen 11 is both faster and longer-lasting Gigi threatens to “have a conniption” if Anwar eats her cinnamon roll when he ambles out of his cottage.īut motherhood is a new phase, and it will be up to Gigi to decide whether it belongs on the silhouette screen of social media. Yolanda hovers by the sink drinking a smoothie and finishing Gigi’s sentences when she grasps for a word. Joining Gigi and Yolanda in the kitchen for lattes and cinnamon rolls before our horseback ride, I witness these roles confirmed. They are a tribe publicly known for their closeness: Yolanda the doting den mother, Gigi the fresh-faced, protective older sister, Bella the edgier Veronica to Gigi’s Betty, and aloof baby brother Anwar. “I decorated fully without my mom’s help, and I think I did her proud,” Gigi says. Gigi got her Christmas tree early for the occasion, dressing it with personal ornaments that she and Malik have exchanged over the years, the most recent being a glass Nintendo console, a reference to a favorite quarantine activity. Bella and Yolanda carted over stuffing and spiked apple cider in the Kubota RTV. Gigi (a prolific home cook herself) made Banoffee pie and baked Yolanda’s favorite tarte tatin. “We’re still close by,” says Gigi, “but we have our space to be our own little family.” She hosted Thanksgiving dinner for the first time this year, with Zayn’s mother, cooking the turkey. It is a family happily in flux: On the sprawling 32-acre property, the handful of cottages are designated for different siblings, but this summer, when Gigi moved out of her cottage into Zayn’s house, Bella and brother Anwar graduated to larger cottages, leaving the smallest as a guesthouse. THE NATURAL TRANSITIONS AND generational shifts of new motherhood are at play in the Hadid household. “You go from looking at her as a daughter to looking at her as a fellow mother.” “I’m proud of her face on a magazine, but seeing her give birth was a whole other level of proud,” Yolanda says. “She decided to completely take care of the baby alone,” says Yolanda, awed, “and I think that bond is so important.” The Dutch former model turned Real Housewives of Beverly Hills alum was my welcoming party when I arrived at the farm, booming “Hello!,” her arms wide on the threshold, in a camo-print puffer and Ugg boots. You’re past the point of the epidural anyway, so you’d be pushing exactly the same way in a hospital bed.’” So she kept pushing. “My midwife looked at me and was like, ‘You’re doing it. “There definitely was a point where I was like, I wonder what it would be like with an epidural, how it would be different,” Gigi says frankly. “I knew it was going to be the craziest pain in my life, but you have to surrender to it and be like, ‘This is what it is.’ I loved that.” Yolanda and the midwife coached Gigi through the pain. Gigi’s Zoom doula, Malibu High classmate Carson Meyer, had prepared her for the moment where the mother feels she can’t go any longer without drugs. It was a way to play with the idea of fantasy in fashion,” says Ethan James Green of his inspiration for this digital cover. When asked to do a cover story for Vogue’s creativity issue, I thought back to that first creative output. “In high school I used to Xerox Steven Meisel’s pictures and color them in with pencil. “Z was like, ‘That’s how I felt! You feel so helpless to see the person you love in pain.’” She then tells me that Malik, the former One Direction star turned solo artist, who is famously press-shy (Gigi’s publicist declined on his behalf to an interview), likened his own experience of her birth to a lion documentary he’d seen in which a male lion paces nervously outside the cave while the lioness delivers her cubs. “That’s something we’d never talked about but in that moment we discovered we both loved,” Gigi says bashfully. He downloaded the film because it was one of his favorites too, and they spent the early hours of labor watching it together. Malik asked Gigi what music she wanted to hear, and she surprised him by requesting the audio of a favorite children’s novel, The Indian in the Cupboard. They placed a blow-up bath in their bedroom and sent their three cats and border collie away when the midwife expressed concern that the sphynx and Maine coon felines might puncture the tub with their claws. QI involves process mapping and systems thinking and the use of measurement and tools to assess, plan, execute and evaluate changes to improve patient and population outcomes, system performance and professional development ( 4, 5). Improvement science has grown out of the wider quality improvement (QI) movement, which entered health care widely in the late 1980s. In parallel, the field of improvement science developed in the 2000s with similar aims of bridging the gap between ideal and actual care to improve health care quality and, thereby, patient and population outcomes ( 2, 3). The ambition is to reduce the research-to-practice gap that is, the gap between what is known through research to be effective and what is actually practiced or used in various areas of society ( 1). Both evidence-based medicine/practice and implementation science address the untapped potential to improve health and welfare of populations through wider and more systematic use of research findings and implementation of empirically supported (“evidence-based”) practices (i.e., clinical interventions, programmes, services, etc.). Within health care research and practice, implementation science has emerged as a vital multidisciplinary research field in the wake of the evidence-based medicine/practice movement. To bridge the silos between the fields, increased collaboration between implementation and improvement scholars will help to clarify the differences and connections between the science and practice of improvement, to expand scientific application of quality improvement tools, to further address contextual influences on implementation and improvement efforts, and to share and use theory to support strategy development, delivery and evaluation. Both apply a range of analytical tools to analyse problems and facilitate appropriate solutions.Ĭonclusions: Implementation science and improvement science have similar endpoints but different starting points and academic perspectives. Both describe problems in terms of a gap or chasm between current and optimal care delivery and consider similar strategies to address the problems. The two fields have different origins and draw mostly on different sources of knowledge, but they have a shared goal of using scientific methods to understand and explain how health care services can be improved for their users. Search methods included systematic literature searches in PubMed, CINAHL, and PsycINFO until October 2021 reviewing references in identified articles and books and the authors' own cross-disciplinary knowledge of key literature.įindings: The comparative analysis of the fields of implementation science and improvement science centred on six categories: (1) influences (2) ontology, epistemology and methodology (3) identified problem (4) potential solutions (5) analytical tools and (6) knowledge production and use. Methods: We used a critical literature review approach. The second objective, building on the first, is to highlight aspects of improvement science that potentially could inform implementation science and vice versa. Objectives: The first objective of this paper is to characterise and contrast implementation science and improvement science. Improvement science has grown out of the wider quality improvement movement, but a fundamental difference between quality improvement and improvement science is that the former generates knowledge for local improvement, whereas the latter is aimed at producing generalizable scientific knowledge. Implementation science was born out of the recognition that research findings and effective practices should be more systematically disseminated and applied in various settings to achieve improved health and welfare of populations. 5Health Service & Population Research Department, Centre for Implementation Science, King's College London, London, United Kingdomīackground: Implementation science and improvement science have similar goals of improving health care services for better patient and population outcomes, yet historically there has been limited exchange between the two fields.4School of Nursing, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.3Sue and Bill Gross School of Nursing, University of California, Irvine, Irvine, CA, United States.2Jönköping University, Jönköping Academy for Improvement of Health and Welfare, Jönköping, Sweden.1Division of Society and Health, Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.Per Nilsen 1 * Johan Thor 2 Miriam Bender 3 Jennifer Leeman 4 Boel Andersson-Gäre 2 Nick Sevdalis 5 While his innocent style was dismissed by many as square and idealized, in 1996 Welk was ranked No. A decade later he died of pneumonia at age of 89. In 1982 Welk retired from both the road and his show, though he produced two Christmas specials over the next few years. design patents for a music-themed restaurant menu, accordion-themed restaurant serving trays and an accordion-themed ashtray. A skilled businessman and investor, he owned a restaurant and club, authored four books and was awarded U.S. Welk’s success wasn’t confined to the bandleader spotlight. At the song’s conclusion, Welk straight-facedly said, “There you’ve heard a modern spiritual by Gail and Dale.” And when he fired his first “Champagne Lady,” Alice Lon, in 1959, the persistent story developed that it was because she displayed too much leg.Īhead of his peers in some ways (he was the first variety show host to regularly feature a black performer), in others Welk was distinctly behind the times, most notably when singers Gail Farrell and Dick Dale cheerily performed the 1971 hit “One Toke Over the Line” with no apparent clue as to its obvious drug reference. Comedians were not invited on the show for fear an off-color joke might slip through nor did Welk use alcohol- or cigarette-related sponsors. Directing a team of solid performers in both standards and pop hits, Welk’s regulars included accordionist Myron Floren, the Lennon Sisters and former Mouseketeer Bobby Burgess.īut while the show’s bubble-accented flow seemed wholesomely effortless, behind the scenes Welk was a stern taskmaster. His greatest success came with The Lawrence Welk Show, which debuted in 1955 and became one of ABC’s most popular shows. Upon reaching that age, Welk took up music full time, playing with several bands before forming his own orchestra, with which he recorded several albums and had a four-year radio show sponsored by Miller High Life Beer. A few years later, his father bought him his own instrument in exchange for the boy’s promise to work on the farm and give his musical earnings to the family until he was 21. A fourth-grade dropout, Welk learned to play his father’s accordion, and by age 13, was performing professionally at local events. Lawrence Welk was born on March 11, 1903, in Strasburg, N.D., on a farm that today is a tourist attraction. The same year, he was nominated for Sound of 2012 by the BBC. American rappers Kanye West and Jay-Z sampled his song I can’t stop in their song Who gon stop me. His use of beats has been received positively by many companies and music artists. Check out Flux Pavilion at The Showbox in Seattle on Septemand get detailed info for the event - tickets, photos, video and reviews. Since first sitting down at a keyboard at the age of six his dream has been to make music that he loves and perform it to people who love it just as much. Flux Pavilion is a British EDM producer/DJ from Towcester, England. Flux Pavilion and NGHTMRE – Feel Your Love feat. Flux Pavilion is a one man orchestra With the ability to Sing and play a large variety of instruments it’s obvious that music comes naturally to him. Get tickets for Flux Pavilion in Seattle, WA at Supernova Seattle on May 25, 2023. Flux Pavilion and Matthew Koma – Emotional (Virtual Riot Remix)ĩ. Flux Pavilion – International Anthem feat. FuntCase and Max Headroom – Let’s Do ItĦ. 64 The Garden of Knowledge 1, 2, 3 : Urszula. Doctor P – Rekt Together (Every Single Night)ģ. Joshua Steele (born 15 January 1989), known professionally as Flux Pavilion, is an English EDM producer, DJ, singer-songwriter and label owner. Flux Park, King's Cross 1, 2, 3, 4, 5 : General Public Agency p. 1 in the ticketing category on Newsweeks list of Best Customer Service in both 20. You can buy Flux Pavilion tickets from Vivid Seats with confidence thanks to the Vivid Seats 100 Buyer Guarantee. Flux Pavilion and DISKORD – Locked In feat. Seattle (9) Denver (9) Austin (7) SF Bay Area (6 ) Appears most with. So experience it live and be there in person for a 2023 Flux Pavilion Dance/Electronica concert. (w/ Flux Pavilion, Doctor P, Cookie Monsta, FuntCase, and DISKORD)ĭec 2 – City National Civic (Bassrush)- San Joseĭec 3 – Belasco Theatre (Bassrush) – Los Angelesĭec 7 – Foundation Nightclub (USC) – Seattleĭec 9 – The Intersection (React) – Grand Rapidsĭec 10 – Cashman Centre (Life in Colour) – Las Vegasġ. Teksupport Produced 104 Dance Events in 2023, But Founder Rob Toma Isn't Ready to Rest: 'You're…Ĭircus Three is available on iTunes, but you can hear a sneak peak, one of the crew’s absolute favorite from the bunch, a laidback, space-age but of bass from Outrun called “Time.” Listen to it below, and check the official Circus Records tour dates along with the full Circus Three tracklist. In fact, SBRT allows prescribing in a limited number of fractions, high dose irradiation to small target volumes, and minimizing the dose exposure to organ at risks (OARs). The combination of both strategies has the purpose to prescribe earlier ablative treatments, prevent local symptoms and postpone the prescription of new systemic treatments. Moreover, in the oligometastatic and oligoprogressive patients, it is progressively becoming current clinical practice to prescribe local ablative radiation treatments (SBRT). Accurate radiological staging, as magnetic resonance imaging (MRI) and metabolic images (PET-CT), allows to detect any metastatic disease presentation earlier. In fact, in the last decades, significant non-invasive technological improvements have been observed in modern radiotherapy. Nonetheless, radiation therapy is still considered one of the important therapeutic options in the management of spinal metastases. Nevertheless, both oncological approaches were associated with a limited local control probability and pain relief. Traditionally, surgical decompression and palliative radiotherapy have been recognized as the main treatment options for these patients. Local back pain and neurological symptoms are the most common clinical disease presentations in spinal metastases. Thus, the evaluated system could be useful in the setting of spinal SBRT to reduce uncertainties of contouring increasing the level of precision on target delivered doses. The dedicated contouring tool allows greater precision and reduction of inter-observer differences in the delineation of the target in SBRT spines. The agreement of GTV contours outlined by independent operators was superior with the use of the automatic contour tool compared to manually outlined contours (mean DICE coefficient 0.75 vs 0.57, p = 0.048). To evaluate the advantage of the automatic target contouring tool (Elements SmartBrush Spine), which uses the identification of different densities within the target vertebra, we evaluated the agreement of the contours of 20 spinal target (2 cervical, 9 dorsal and 9 lumbar column), outlined by three independent observers using the automatic tool compared to the contours obtained manually, and measured by DICE similarity coefficient. Simulation CT scans and MRI data of 20 patients with spinal metastases were evaluated. In this study, an automatic contouring tool was evaluated. An automatic target contouring system for spine SBRT is useful to reduce inter-observer differences in target definition. Due to the high delivered doses and the proximity of critical organs at risk (OAR) such as the spinal cord, the correct definition of the treatment volume becomes even more important in SBRT treatment, thus making it necessary to standardize the method of target definition and contouring, through the adoption of specific guidelines and specific automatic contouring tools. Stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT) have been offered in clinical practice mainly for the management of oligometastatic and oligoprogressive patients, allowing the prescription of high total dose delivered in one or few sessions to small target volumes, minimizing the dose exposure of normal tissues. Approximately one third of cancer patients will develop spinal metastases, that can be associated with back pain, neurological symptoms and deterioration in performance status. Hopefully this will work so that you will not have to call them again. 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